Transgenic mice express a FLAG-tagged type III isoform of human CIITA under the control of a CD4 promoter/enhancer cassette. Expression of the transgene is detected in CD4-positive T cells. An additional line, line 400, was also generated and shows a similar phenotype to line 357. (J:99357)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J x SJL
--
Insertion
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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