Transgenic mice express a FLAG-tagged type III isoform of human CIITA under the control of a CD4 promoter/enhancer cassette. Expression of the transgene is detected in CD4-positive T cells. An additional line, line 400, was also generated and shows a similar phenotype to line 357. (J:99357)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count