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The P25TCR transgenic mice contain a T-cell antigen receptor (TCR) that recognizes peptide 25 (aa 240-254) of Mycobacterium tuberculosis Antigen 85B bound to I-Ab under the control of the H-2Kb promoter. Specifically, two transgenes were created, each containing either cDNA encoding the Valpha5 or the Vbeta11 gene, and a polyadenylation (polyA) sequence. Line P25 was created. (J:94023)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
