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The transgene contains a 14.2 kb fragment from the 14.5 kb genomic rat AOGEN clone. Three lines were created (lines 92, 102, and 123) with line 123 exhibiting a 4-fold increase in plasma angiotensinogen and ANGII levels. (J:160282)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
