The targeting vector contains a loxP-flanked neomycin cassette inserted in intron 2 and a loxP site flanking exon 2. Mice were crossed with mice carrying Tg(EIIa-cre) to remove the neo cassette leaving two loxP sites flanking exon 2. (J:160208)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count