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The full length coding sequence of recombined mouse Tcra from mouse hybridoma 2E7 uses Tcra-V9 and was placed under the control of the Cd2 promoter while the full length coding sequence of recombined mouse Tcrb from mouse hybridoma 2E7 uses Tcrb-V11 and was placed under the control of the Cd4 promoter. The two constructs were coinjected into single celled NOD embryos. CD4+ T cell hybridoma 2E7 contains T cell receptors specific for a peptide of Mpz (P0) containing the first 25 amino acids following the signal peptide. (J:146797)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
