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The transgene contains the CMV enhancer/chicken beta-actin promoter, a floxed beta-geo reporter/SV40 polyadenylation signal segment, and murine Lhx2 cDNA, an internal ribosomal entry site (IRES) and green fluorescent protein (GFP) followed by a rabbit Hbb polyadenylation sequence. The cells with the highest lacZ expression and a single integration were selected for blastocyst injection. (J:159209)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
