A portion of exon 6, intron 6 and a part of exon 7 were replaced with a LacZ-Neo cassette by homologous recombination. Northern blot and Western blot analysis revealed a complete loss of message and protein, respectively, in homozygous mice. (J:158491)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count