Lox511 sites were inserted in the intron between exon 1C and exon 1B as well as in intron 2 just downstream of an frt flanked neomycin insert. The neomycin selection cassette was subsequently excised in mice by crossing to transgenic mice expressin Flp recombinase. (J:159972)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count