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EN
The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 2434 bp between positions 60668857-60671290 of Chromosome 11 (Build GRCm39). The gene locus is partially replaced by a cassette containing lacZ-polyA followed by a loxP-flanked hUbCpro-neo-polyA sequence. RT-PCR and Western blot analyses confirmed the absence of mRNA and protein expression in mouse embryonic fibroblasts (MEFs) derived from homozygous mutant embryos. (J:136110, J:236977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
