A targeting vector was designed to insert a loxP site upstream of the coding sequence in exon 1, followed by an frt-flanked neomycin resistance (neo) cassette and a second loxP site upstream of exon 2 of the wntless homolog (Drosophila) (Wls) gene. Flp mediated recombination removed the neo cassette leaving the coding sequence of exon 1 floxed. (J:164701)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
1
67

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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