The first 434 coding base pairs of the single exon with a 5' loxP site was followed by SV40 PolyA signal with a downstream loxP site, and followed by a PGK neomycin selection cassette. Homozygous mice showed significantly reduced mRNA levels in mammary glands, although no apparent developmental or functional differences were observed. (J:159517)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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