A loxP site was inserted upstream of exon 5 and another downstream of exon 7; a PGK-neo/HSV-tk cassette (neo/tk) followed by a third loxP site was inserted in intron 7 further downstream. The present allele was generated by Cre recombinase excision of the neo/tk cassette and exons 5 through 7 of the endogenous gene. (J:159441)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count