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The 15 base pairs in exon 1 encoding enterostatin, a pentapeptide (APGPR) produced from cleavage of the pro-colipase peptide, were removed. A floxed neo cassette was also inserted into intron 1 and subsequently removed by cre mediated recombination. Normal expression of a slightly smaller colipase protein was confirmed by western blot analysis on pancreas extracts. Enzymatic assay confirmed normal colipase activity. (J:159587)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
