Exons 3-5 were disrupted by insertion of a cassette containing GFP (in frame) and neo (in reverse orientation). No GFP expression was detected in lung or peripheral blood. The absence of protein expression was confirmed by western blot analysis on splenocyte extracts. (J:158011)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count