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Aspartic acid codon 56 (GAC) the integrin-binding RGD sequence in exon 4 was changed to glutamic acid (GAG) (p.D56E). The protein product is predicted to be deficient in integrin-binding. A loxP flanked neomycin resistance gene cassette used for selection was removed by Cre-mediated recombination. (J:159246, J:173933)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
