A lacZ and floxed neo cassette were inserted into an NcoI site in exon 1 that includes the start site via homologous recombination. The neo was removed by Cre mediated recombination. RT-PCR confirmed the absence of transcript in homozygous mice. (J:158888)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count