Log In|Sign Up
EN
A human BCL2L1 cDNA was cloned under the regulatory control of the SV40 promoter and the IgH enhancer (Emu). The 2.4-kb fragment containing the SV40-Emu-bcl-xL insert was microinjected into F2 hybrid zygotes from (C57BL/6 x SJL/J)F l parents. Three founder mice expressing the human cDNA BCL2L1 in lymphoid tissue, as determined by Western blot analysis, were recovered. Expression was restricted to the B-cell compartment in Line 87. (J:31310)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
