An frt flanked neo cassette and loxP site were inserted upstream of exon 1 and a second loxP site was inserted downstream of exon 1 vi homologous recombination. The neo cassette was then removed by Flp mediated recombination. (J:158898)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count