Two loxP sites were inserted to flank exon 3 of the gene, followed by an SA-IRES-lacZ-neo-SVpA cassette and a third loxP site after the cassette in intron 3. The SA-IRES-lacZ-neo-SVpA cassette was deleted by Cre mediated recombination. (J:158671)
Basic Information
(C57BL/6 x 129P2/OlaHsd)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count