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Two loxP sites were inserted to flank exon 3 of the gene, followed by an SA-IRES-lacZ-neo-SVpA cassette and a third loxP site after the cassette in intron 3. Northern blot analyses revealed aberrant mRNA expression. Immunoblot analysis showed the absence of the full-length protein; a truncated N-terminal fragment was below the detection limit. (J:158671)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
