A loxP site was inserted upstream of the exon encoding part of the DNA polymerase motif 1 and downstream of the exon encoding all of the DNA polymerase motif 5. A floxed neo cassette used for cell selection was removed by cre-mediated recombination leaving the floxed region intact. (J:158922)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count