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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Bhlhe22
tm3.1(cre)Meg
Alias:
B5-cre
Bhlhe22-Cre
Bhlhb5-cre
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Basic Information
Phenotypes
References Literature
The coding region of the Bhlhe22 gene was replaced by the coding sequence of cre recombinase and a loxP flanked neo selection cassette via homologous recombination in ES cells. The neo was removed in the ES cells by cre-mediated excision. (J:158273)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
4440745
129/Sv
Targeted
Insertion, Intragenic deletion
--
1
--
13
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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