The targeting vector used to generate the Nkx6-2tm1Ercs allele was modified by replacing the lacZ/PGKneo cassette with a cre/PGKneo cassette. The same strategy as described in J:71607 was followed to generate this Nkx6-2 mutant allele using the modified targeting vector. (J:131770)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intragenic deletion
--
1
1
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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