An N-terminal FLAG tag was added after the start codon within exon 2 and a single loxP site was inserted in intron 1 within the 5' UTR. A loxP flanked neo was inserted within intron 5. Expression level of flag tagged protein is low. Northern blot analysis revealed that there were multiple transcripts present with a significant reduction of the mature transcript. (J:158394)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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