A loxP site was inserted into intron 1 and an FRT site flanked neomycin reistance gene cassette with a 5' loxP site was inserted into intron 2. Flp-mediated recombination removed the neo cassette, leaving exon 2 floxed. (J:158406)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count