A loxP site was inserted into exon 1 upstream of the start site and an frt flanked neo cassette and second loxP cassette were inserted into intron 1. Flp mediated recombination removed the neo cassette. (J:157924)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count