This transgene expresses the human TSHR alpha-subunit cDNA (amino acid residues 1-289) with a 6-histidine tag under the control of the bovine thyroglobulin promoter. Human TSHR alpha-subunit expression, analyzed by RT-PCR, is detected in thyroid tissue from transgenic mice. Lines 51.9 and 60.6 were also generated. (J:118100)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(BALB/c x C57BL/6)F1
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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