A construct composed of the 9.2 kb Alk1 regulatory fragment (containing a 2.7 kb promoter region and exon1-3 of Alk1), the SV40 splicing donor and acceptor (SD/SA), an internal ribosome-entry site (IRES), a polyadnylation signal and the cre recombinase sequence was used to generate the B1 transgenic cre line, as well as three other founder lines including the L1- and D-lines. B and D lines showed similar staining patterns when crossed to lacZ reporter animals. (J:130020)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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