From 5' to 3' the tansgene contains a synthetic polyadenylation site, the rat myosin light chain 1 gene promoter, the cre recombinase gene modified to contain a Kozak consensus site immediately upstream of the start codon, intron and polyadenylation sites from the SV40 t antigen gene, and the rat myosin light chain 1/3 enhancer. A line was chosen that exhibited skeletal muscle-specific expression as determined by Northern analysis. (J:158173)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x SJL/J)F1
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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