An EGFP-IRES-CreERT2 cassette was inserted at the transcriptional start site along with a loxP-flanked neomycin cassette by homologous recombination. The neomycin gene was then removed by cre mediated recombination. EGFP expression is driven by the endogenous promoter. Cre expression is induced by tamoxifen treatment. (J:157895)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count