Exon 2 was flanked by loxP sites and a FRT flanked neo marker was inserted in intron 2 by homologous recombination. The selection cassette was deleted by Flpe recombinase. (J:157532)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count