A loxP site was inserted upstream of the coding region and a floxed neo cassette was inserted downstream. Cre mediated recombination removed the neo cassette leaving the coding region floxed. (J:157537)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count