A targeting vector containing an rtTA cassette and a floxed neo cassette was inserted at 32 bp upstream of the transcription start site, putting the transactivator protein under the control of the olfactory-specific endogenous promoter. Induction with doxycycline resulted in robust expression that was restricted to the olfactory mucosa and inducer-dependent. (J:157842)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count