A dominant active form of Akt1 with a c-Src myristoylation sequence and a hemagglutinin tag added to the N-terminus was inserted behind a tetracycline-responsive promoter (tetO). Two lines were tested and displayed similar performance. Line K8 was studied further. (J:95750)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count