A GFP gene cassette was inserted 8 bp upstream of the start codon and a neo gene in reverse orientation was inserted 110 bp downstream of exon 2 resulting in the replacement of the coding region of exon 2 and part of intron 2. RT-PCR detected no transcript in homozygous mice and GFP was expressed. (J:157256)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv
Targeted
Insertion, Intragenic deletion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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