The GFAP-HD transgene was designed containing 208 aa of N-terminal human huntingtin (HTT) gene, containing 160 glutamine residues (160Q), driven by the human glial fibrillary acidic protein (GFAP) promoter, followed by a mouse protamine-1 (MP-1) polyadenylation (polyA) signal. (J:156460)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NCrl
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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