The GFAP-HD transgene was designed containing 208 aa of N-terminal human huntingtin (HTT) gene, containing 160 glutamine residues (160Q), driven by the human glial fibrillary acidic protein (GFAP) promoter, followed by a mouse protamine-1 (MP-1) polyadenylation (polyA) signal. (J:156460)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count