Exon 4 was replaced with a construct containing the following elements: loxP site, exon 4, IRES, GFP, loxP, neo cassette, and loxP site. Cre mediated recombination removed the neo cassette leaving exon 4 following by an IRES sequence and GFP gene floxed. (J:157076)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count