Exon 4 was replaced with a construct containing the following elements: loxP site, exon 4, IRES, GFP, loxP, neo cassette, and loxP site. Cre mediated recombination removed the neo cassette leaving exon 4 following by an IRES sequence and GFP gene floxed. (J:157076)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion
--
1
5
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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