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The transgene construct contained a 3.4 kb fragment of the cre recombinase sequence dowstream of the 1.5 kb rat Abpa promoter. This was followed by the metallothionein I (MT-1) sequence with polyA signal. The purified, linearized construct was injected into fertilized B6D2F1 oocytes. 10 founders were obtained, with 9 showing testicular cre mRNA expression. One line was propagated. (J:157337)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
