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A 1.6 kb fragment encoding cre recombinase followed by the rabbit beta-globin polyadenylation signal was used to generate a targeting vector that replaced the translational start site of Foxl2 with the cre-ATG start codon by homologous recombination. The targeting vector contained a self-excising neo cassette (ACN cassette) and a diphtheria toxin-negative selection cassette (DTA). The ACN cassette was excised during passage through the male germline. (J:157008)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
