Homologous recombination in ES cells was utilized to replace the endognenous Foxl2 sequence with a hemagglutinin (HA)-tagged Foxl2 cDNA and a self-excising neo selection cassette (ACN). The neo cassette was excised in the male germline. (J:157008)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count