A targeting vector was used to insert loxP sites to flank the single coding exon of the Foxl2 locus by homologous recombination in ES cells. An FRT-flanked neomycin selection cassette introduced during recombination was removed by Flp-mediated recombination, leaving a single residual FRT site. (J:157008)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count