A transgenic construct encoding cre recombinase with mutated estrogen receptor ligand-binding domains (Esr1, Mer) at the N- and C-termini (MerCreMer) under control of the CAG promoter was injected into B6DF1 fertilized eggs to generate CAG-MerCreMer mice. (J:157054)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count