A loxP-flanked transcriptional stop signal in the antisense direction was inserted into intron 6. Exon 7 was fused to exons 5-9 of human FLI1 with a C-terminal FLAG tag, and a 3' neo cassette, replacing exons 8 through 11 by homologous recombination. The absence of endogenous protein product was confirmed by western blot analysis. (J:156860)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Intragenic deletion
--
1
6
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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