LoxP sites were introduced into the first and third introns, permitting deletion of exons 2-3 by Cre recombinase. Flp-mediated recombination removed the FRT-flanked neo cassette inserted into the first intron. (J:173672)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count