A loxP site was inserted upstream of exon 3, and a pgk-neo cassette flanked by FRT sites as well as a second loxP site were targeted downstream of exon 7. Chimeric mice were produced from two recombinant ES cell clones. (J:156018)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count