This deletion was created by cre mediated recombination of loxP sites within Sparc (created by eliminating exon 6 and replacing it with a Neo-LoxP as well as inserting stop codons in all three reading-frames) and beyond Gpx3 (created by random insertion vector of loxP-Puro cassette). The deletion spans an interval of between 0.7 Mb to 1.5 Mb, between Sparc and Gpx3 and includes Fat2, Gm2a, Anxa6, and Tnip1. (J:155870)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion, Intergenic deletion, Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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