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The construct contained a 2.1 kb fragment of the human KRT14 promoter, rabbit beta-globin intron, and EGFP/beta-actin cDNA. followed by KRT14 3' untranslated and polyadenylation sequences. Seven founders were obtained and 2 lines were propagated. Transgene expression occurs in mitotically active epidermal cells.For founder line 50, around 2-3% of total actin was made up of transgenic GFP-actin. (J:156846)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
