This allele was generated by inserting an EGFP-IRES-loxP-FRT sequence into the 5' UTR of the En2 locus immediately upstream of the ATG and a loxP site into the intron. An FRT-flanked neo cassette was removed by flp mediated recombination. Cre recombination deleted the En2 sequence, producing a null allele with a GFP reporter. (J:156169)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
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1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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