The Dlx5/6-FLPe transgene was designed with the intergenic enhancer region between the mouse Dlx5 and Dlx6 (id6/id5, mI56i) locus together with a beta-globin basal promoter, a chimeric intron containing a human _-globin splice donator site and IgHC variable region splice acceptor site, a FLPe site-specific recombinase with Myc tag (FLPeMyc) sequence, and SV40 early mRNA polyadenylation signal cassette. This transgene was microinjected into FVB/N mouse cells. Mice from founder line 39 were mated with outbred Swiss Webster mice for many generations. (J:156662)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
--
--
26

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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