A concatemer of sleeping beauty transposable elements each consisting of optimized inverted repeat direct repeat sequence specific for sleeping beauty transposase flanking splice acceptor sites (from engrailed-2) and poly A signals in both orientations. Between the splice acceptor sites is the sequence for the CAG promoter followed by a splice donor site. Two lines were created (lines 12740 and 12775) with 11 and 28 copies of the transgenic transposon concatemer inserted into chromosome 9 and 12, respectively. (J:153656)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count